Childhood mortality remains high in low-resource settings, where environmental enteric dysfunction (EED) is prevalent. Peripheral blood bacterial lipopolysaccharides (LPS) are potential biomarkers of intestinal microbial translocation and inflammation; however, the effects of LPS translocation on mortality in this context remains unexplored. Read full article here
Abstract
In resource-limited settings, children often experience poor growth following illness, but the mechanisms are poorly understood. This cohort study in six countries in sub-Saharan Africa and south Asia investigates pathways linking inflammation and post-discharge weight gain among children hospitalised with acute illness. Read full article here
The Childhood Acute Illness and Nutrition Network (CHAIN) is a multinational research group that aims to optimize the management and care of highly vulnerable children in resource-limited settings to improve survival, growth and development.
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