CHAIN NETWORK

The Childhood Acute Illness & Nutrition Network

A group of clinical experts, scientists and advisors worldwide seeking to optimize care for vulnerable children in limited resource settings

Highlights

 

CHAIN Results

The CHAIN cohort study found that young children in sub-Saharan Africa and South Asia who become sick or malnourished continue to have a high risk of death in the six months after being hospitalized.

To learn more about findings from the CHAIN cohort study, please visit:
https://chain.tghn.org/
https://chain.tghn.org/chain-study-toolkit-community/

Click Here to Read the full publication paper

 

Watch our CHAIN webinar “Childhood mortality during and after illness”:

On the Front line

We are delighted to share a new video created by our early career researchers and Al Davies called ‘On the Frontline’. It explores the idea of frontline researchers as a critical bridge between communities and research institutions and funders, offering important insights into the ethical dilemmas they face while also challenging simplistic generalisations about ‘vulnerable populations’ in the research context. Hats off to the team for adapting to the limits of lockdown around the world and lending their creativity and voices to this work! Please do share across your networks and feel free to use in teaching/training sessions:

The CHAIN Network is  focused on optimizing the management and care of the sick and undernourished child in  resource-limited settings to improve survival, growth and development.

The CHAIN Network aims to identify the biological mechanisms and the socio-economic factors that determine a child’s risk of mortality in the six months following presentation to medical care with an acute illness.

Clinical Sites

Partner Sites

Coordination Sites

 

The CHAIN Network aims to identify the biological mechanisms and the socio-economic factors that determine a child’s risk of mortality.

Recent Research

Toll-Like Receptor-Induced Immune Responses During Early Childhood and Their Associations With Clinical Outcomes Following Acute Illness Among Infants in Sub-Saharan Africa

| CHAIN Publications | No Comments
Abstract Severely ill children in low- and middle-income countries (LMICs) experience high rates of mortality from a broad range of infectious diseases, with the risk of infection-related death compounded by…

Childhood mortality during and after acute illness in sub-Saharan Africa and South Asia – The CHAIN cohort study

| CHAIN Publications | No Comments
Abstract Objectives Mortality during acute illness among children in low- and middle-income settings remain unacceptably high and there is increasing recognition of the importance of post-discharge mortality. A comprehensive understanding of…
 

The Network will serve as a platform for substantive clinical trials that are led within the group in order to inform policy

The CHAIN Network is funded by the
All Partners